There are many choices of medicines to treat type 2 diabetes. There are Metformin, Insulin glargine, Sulfonylureas, and Liraglutide. Let’s explore them. Which one works best for you? Find out here! In this article, you will learn about the advantages and disadvantages of each type of medicine. Read on to find out which medicine suits your needs best.
Metformin
In the current market, metformin is the best medicine for type 2 sugar ki dawai. The drug’s effectiveness is based on its ability to improve the body’s response to insulin. The drug costs as little as $0.06 per day. It has the advantage of being cheap, as it is available over the counter at local drug stores.
However, the mechanism of action of metformin is still debated. Recent data suggest that the drug may have some effects through the stimulation of incretin hormones in the intestine. The current evidence is insufficient to make a definitive conclusion. However, a new meta-analysis of metformin clinical trials suggests that it has a good cardiovascular effect. Although metformin is the best medicine for type 2 diabetes, it is not the only diabetes treatment.
Fortunately, metformin is generally considered safe for most people. While it can cause diarrhea, most of these effects are mild, transient, and dose-related. Although only 5% of patients cannot tolerate metformin at the recommended dose, it is worth considering that some patients may experience severe side effects. If you are one of these people, talk to your healthcare provider to see if this medication is safe for you.
Although metformin can cause some side effects in some people, it has been approved by the U.S. Food and Drug Administration (FDA) in 1994 and has become the medication of choice for many type 2 diabetics. The medication works well at lowering blood sugar levels, and even a small increase in dose can lead to a significant reduction in the risks of diabetes-related complications. If you are taking metformin for the first time, your health care provider may want to try it again. You can start with a lower dose and work your way up as your blood glucose levels improve.
Insulin glargine
People with liver or kidney disease may not produce enough glucose or may have trouble breaking down insulin glargine. Alcohol is another risk because it may impair blood sugar control. And don’t give insulin glargine to anyone else, as it could harm them.
The drug is a long-acting analog of human insulin, which is produced by a strain of nonpathogenic Escherichia coli. Insulin glargine differs from human insulin by adding two arginine amino acids to its C-terminus. It also replaces the arginine at position A21 with glycine. This change in amino acid sequence makes insulin glargine more soluble at acidic pH levels than at neutral pH levels. It forms a precipitate in the subcutaneous tissue.
In the United States, insulin glargine is available as an injectable solution. The brand-name drug is Lantus, while the generic version is Basaglar. The two insulins are similar but different and do not share the same characteristics. Despite this difference, Lantus is the best medicine for type 2 diabetes. However, there is a risk of side effects.
This drug showed improved glycemic control in two clinical trials. It significantly reduced mean fasting blood glucose levels, reducing fasting levels by 2.2 mmol/L. This drug was also associated with less hypoglycemia, especially nocturnal hypoglycemia when compared to once-daily NPH insulin. If you’re looking for a type 2 diabetes medicine, insulin glargine is a good option.
Sulfonylureas
Research has focused on determining which drug or anti-hyperglycemic agent is the best medicine for type 2 diabetes. This is a complex question because it is difficult to predict when patients will become dependent on a particular medication. Further, it is unclear how a patient will respond to a sulfonylurea if they become dependent on the drug.
While the safety of sulfonylureas as first-line treatments has been extensively studied, the evidence is still insufficient to determine whether they can be safely prescribed for patients who have failed metformin monotherapy. Also, patients on second-generation sulfonylureas are at an increased risk of developing heart failure and having a myocardial infarction. This is why patients should avoid switching to these drugs unless they are absolutely necessary.
Although sulfonylureas are the best medicine for type 2 diabetes, there are several contraindications to using them. They may increase the risk of heart attacks and all-cause mortality. They can also increase the risk of severe hypoglycemia. This is why it’s important to consult with your doctor about any risks associated with sulfonylureas before starting any new medication.
Combining different sugar bimari ka ilaj medicines can help you control your blood sugar better. Biguanide and sulfonylurea can work together for a better overall effect. Taking more than one drug can be expensive and increase your risk of side effects. Taking a combination of two or more medications can help you better manage your blood glucose levels and improve your quality of life.
Liraglutide
In a recent study, researchers discovered that liraglutide is the best medicine for type two diabetes. Liraglutide improved hemoglobin A1C levels by 0.65 percentage points while reducing HbA1C in the placebo group by 0.42 percentage points. The liraglutide group also had higher fasting glucose than the placebo group, which was consistent with earlier studies.
In the study, liraglutide significantly reduced levels of both systolic blood pressure and very low-density lipoprotein cholesterol. The liraglutide treatment also improved the function of b-cells. In addition, it significantly decreased insulin resistance (measured by HOMA) in all three treatment groups. This resulted in reduced levels of these two drugs.
A recent study of 134 patients with type 2 diabetes used liraglutide to lower fasting glucose levels. The medication was equally effective compared to a placebo. In addition, the doses of liraglutide were similar compared to placebo. However, the liraglutide-treated patients experienced lower levels of glycated hemoglobin than those in the placebo group.
The GRADE study used a highly diverse patient population, including patients of all ages, races, and ethnicities. Because minority groups are disproportionately affected by diabetes, the study included people from minority groups. Twenty percent of the patients were Black or Hispanic/Latino Americans. One of the study sites, the UNC Diabetes Care Center, also had people who spoke Spanish. Researchers followed the patients for an average of five years but could enroll those who spoke Spanish fluently.
Bydureon BCise
Bydureon BCise is an oral medication that is available for the treatment of type 2 diabetes. It can be given at any time, with or without food. However, you must discuss all the details with your healthcare provider. It comes in four single-dose auto-injectors, with a pen version being discontinued in 2021. It is safe to use, but you may experience side effects, including nausea, vomiting, and dizziness.
BYDUREON is usually injected once a week, but you may be required to change the day if your next dose is three days away. It is important to avoid mixing BYDUREON and insulin because the two should not interact with one another. If you miss a dose, take it as soon as you remember it, otherwise, you need to wait until your next regularly scheduled dose. You can also choose a preferred day of the week for injection.
Bydureon has several side effects, such as increased blood glucose or lower blood sugar levels. It is also associated with gallbladder problems and may require dosage adjustment. It may cause diarrhea, constipation, or swelling of the legs. Other side effects include nausea and fatigue, as well as vomiting and diarrhea.
The drug’s active ingredient, exenatide, can cause adverse effects when administered to pregnant mice. Exenatide can be toxic to both the mother and the fetus. As such, it should be used only if the potential benefit outweighs the risk. Bydureon BCise is the best medicine for type 2 diabetes
